Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | USP2 | O75604 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 6/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.51 |
| ▸ | RECQL | P46063 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | RGS12 | O14924 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11713473 | 0.85 | NPC1 (0.66) | KMT2AMEN1USP2MAPTKEAP1 | |
| SCHEMBL11711964 | 0.83 | KMT2A (0.52) | KMT2AMEN1USP2MAPTKEAP1 | |
| SCHEMBL11712893 | 0.82 | KMT2A (0.56) | KMT2AMEN1USP2MAPTKEAP1 | |
| SCHEMBL11715092 | 0.82 | MEN1 (0.54) | KMT2AMEN1USP2MAPTKEAP1 | |
| SCHEMBL11711675 | 0.82 | KMT2A (0.54) | KMT2AMEN1USP2MAPTKEAP1 | |
| SCHEMBL11245313 | 0.81 | KMT2A (0.56) | KMT2AMEN1USP2MAPTKEAP1 | |
| SCHEMBL11720160 | 0.81 | KMT2A (0.64) | KMT2AMEN1USP2MAPTKEAP1 | |
| SCHEMBL11712190 | 0.80 | MEN1 (0.55) | KMT2AMEN1USP2MAPTKEAP1 | |
| SCHEMBL11720188 | 0.80 | KMT2A (0.52) | KMT2AMEN1USP2MAPTKEAP1 | |
| SCHEMBL28305410 | 0.80 | ERCC1 (0.55) | KMT2AMEN1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |