Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260411 | 0.85 | HTT (0.43) | MEN1KMT2AMAPK1HTTNPC1 | |
| SCHEMBL11252255 | 0.83 | HTT (0.40) | MEN1KMT2AMAPK1HTTNPC1 | |
| SCHEMBL11262102 | 0.80 | MAPK1 (0.43) | MEN1KMT2AMAPK1HTTNPC1 | |
| SCHEMBL11050902 | 0.79 | MAPK1 (0.49) | MEN1KMT2AMAPK1HTTNPC1 | |
| SCHEMBL11048657 | 0.79 | HTT (0.47) | MEN1KMT2AMAPK1HTTNPC1 | |
| SCHEMBL11053938 | 0.79 | HTT (0.47) | MEN1KMT2AMAPK1HTTNPC1 | |
| SCHEMBL11255736 | 0.79 | HTT (0.41) | MEN1KMT2AMAPK1HTTNPC1 | |
| SCHEMBL11053827 | 0.77 | MAPK1 (0.54) | MEN1KMT2AMAPK1HTTPOLB | |
| SCHEMBL11049975 | 0.77 | HTT (0.48) | MEN1KMT2AMAPK1HTTNPC1 | |
| SCHEMBL11256689 | 0.77 | CRBN (0.31) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |