Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18304358 | 0.83 | MAOB (0.62) | MAOBMAPTRAB9ANPSR1MAOA | |
| SCHEMBL11238714 | 0.83 | MAPT (0.58) | MAOBMAPTRAB9ANPSR1MEN1 | |
| SCHEMBL4321498 | 0.80 | MAPT (0.65) | MAOBMAPTRAB9ANPSR1MAOA | |
| SCHEMBL11249195 | 0.79 | MAPT (0.49) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL2965418 | 0.79 | MAOB (0.63) | MAOBMAPTRAB9AMAOACHRNB2 | |
| SCHEMBL30443578 | 0.79 | MAOB (0.63) | MAOBMAPTRAB9AMAOACHRNB2 | |
| SCHEMBL21384019 | 0.79 | RXRA (0.56) | MAOBRAB9AMAOAKMT2ANPC1 | |
| SCHEMBL18429630 | 0.78 | APP (0.59) | MAOBMAPTRAB9ANPSR1MAOA | |
| SCHEMBL9795659 | 0.78 | MAOB (0.62) | MAOBMAPTRAB9ANPSR1MAOA | |
| SCHEMBL2960397 | 0.78 | MAPT (0.66) | MAOBMAPTRAB9ANPSR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332944-A | Compositions and use | ZOECON CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |