Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | BRD4 | O60885 | 4/20 | 0.55 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.55 |
| ▸ | BRD2 | P25440 | 2/20 | 0.55 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.55 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.52 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.52 |
| ▸ | BPTF | Q12830 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245399 | 1.00 | NPC1 (0.62) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL11239943 | 0.87 | BRD4 (0.53) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL11239947 | 0.87 | BRD4 (0.53) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL11239449 | 0.87 | BRD4 (0.55) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL11239443 | 0.87 | BRD4 (0.55) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL11236338 | 0.84 | NPC1 (0.72) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL11236335 | 0.84 | NPC1 (0.72) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL15496642 | 0.83 | BRD4 (0.66) | MAPTL3MBTL1BRD4BRD3BRD2 | |
| SCHEMBL11242221 | 0.82 | BRD4 (0.64) | NPC1RAB9AMAPTBRD4BRD3 | |
| SCHEMBL11242226 | 0.82 | BRD4 (0.64) | NPC1RAB9AMAPTBRD4BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323682-A | BLEACHING CATALYSTS | CIBA GEIGY AG (CH) | 1982-04-06 | — | — | US | disclosed |
| US-4202698-A | DYE BLEACH CATALYSTS | CIBA-GEIGY AG (CH) | 1980-05-13 | — | — | US | disclosed |