Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSC | P53634 | 2/20 | 0.52 |
| ▸ | CTSF | Q9UBX1 | 2/20 | 0.52 |
| ▸ | CTSH | P09668 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245488 | 1.00 | CTSV (0.52) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL11250765 | 1.00 | CTSV (0.52) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL11250731 | 1.00 | CTSV (0.52) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL11245479 | 1.00 | CTSV (0.52) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL11237393 | 0.83 | CTSV (0.52) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL11237384 | 0.83 | CTSV (0.52) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL11237386 | 0.83 | CTSV (0.52) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL11241262 | 0.83 | CTSV (0.52) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL11241271 | 0.83 | CTSV (0.52) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL11248237 | 0.79 | CTSV (0.50) | CTSVCTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320137-A | Derivatives of perhydro-aza-heterocycles | CIBA-GEIGY CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |
| US-4246269-A | Antidepressant piperidinones | CIBA-GEIGY CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| US-4160837-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |