CTSV — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL312542	0.66	8/20
SCHEMBL311524	0.75	7/20
SCHEMBL159283	0.60	6/20
SCHEMBL472872	0.54	6/20
SCHEMBL367268	1.00	5/20
SCHEMBL312847	0.67	5/20
SCHEMBL582235	0.60	5/20
SCHEMBL248836	0.59	5/20
SCHEMBL312866	0.57	5/20
SCHEMBL582525	0.50	5/20
SCHEMBL472759	1.00	4/20
SCHEMBL339070	0.62	4/20
SCHEMBL273831	0.56	4/20
SCHEMBL311746	0.55	4/20
SCHEMBL312386	0.53	4/20
SCHEMBL527106	0.52	4/20
SCHEMBL546035	0.50	4/20
SCHEMBL312037	0.45	4/20
SCHEMBL464043	0.43	4/20
SCHEMBL354532	1.00	3/20

Clinical trials — most relevant to CTSV by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Efficacy and Safety of Favipiravir and Ribavirin Formulation for Treatment of COVID-19	PHASE2/PHASE3	UNKNOWN
DEFINE - Evaluating Therapies for COVID-19	PHASE1/PHASE2	COMPLETED
A Phase II Single-arm Intervention Trial of Nelfinavir in Patients With Grade 2/3 or 3 Cervical Intraepithelial Neoplasia	PHASE2	WITHDRAWN
Investigation the Effect of Montelukast in COVID-19	PHASE2	UNKNOWN
Study of CTS-1027 in Hepatitis C Patients	PHASE2	COMPLETED
Favipiravir vs Hydroxychloroquine vs Control in COVID -19	PHASE2	COMPLETED
Safety and Antiviral Activity of BLD-2660 in COVID-19 Hospitalized Subjects	PHASE2	COMPLETED
The Study of Quadruple Therapy Quercetin, Zinc, Metformin, and EGCG as Adjuvant Therapy for Early, Metastatic Breast Cancer and Triple-negative Breast Cancer, a Novel Mechanism	EARLY_PHASE1	UNKNOWN
Respiratory Cathepsins, Proteases Inhibitors and Glycosaminoglycans (GAG) in Mucopolysaccharidosis	nan	COMPLETED
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence	nan	WITHDRAWN
Association Between Periodontitis and Coronavirus Disease (COVID-19)	nan	COMPLETED
Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients	nan	RECRUITING
Diagnostic Value of Serum Cathepsin S and Chromogranin A in DKD	nan	NOT_YET_RECRUITING
Turkish Adaptation of the CTS-6 Evaluation Tool: A Validation and Reliability Study	nan	NOT_YET_RECRUITING
Hematological Markers in Idiopathic Carpal Tunnel Syndrome	nan	COMPLETED
Multimodal Approach of Electrotherapy Versus Nerve Flossing Technique in Patient With Carpal Tunnel Syndrome	nan	UNKNOWN
Screening of Lysosomal Storage Disorders Diseases in Minority Groups	nan	UNKNOWN
SRT in Comparison to ERT on Immune Aspects and Bone Involvement in Gaucher Disease	nan	UNKNOWN
Fasting, Exercise, and Diet to Activate Autophagy in Depression	nan	NOT_YET_RECRUITING
Predicting Pancreatic Necrosis Using mitDNA	nan	UNKNOWN
Chemokine Mechanisms in Chronic Pelvic Pain	nan	COMPLETED
The Role of Vitamin K2 in Preventing Glucocorticoid-Induced Bone Loss in Children With Nephrotic Syndrome	nan	RECRUITING
Lung HIV Disease in a Large Cohort-Pitt	nan	COMPLETED
Ontogenesis of the P-Glycoprotein in Human Lymphocytes Influence of HIV and Antiretroviral Therapeutics	nan	COMPLETED
Ultrasound Measures and Clinical Outcomes in Healthy Individuals, Mild and Moderate Carpal Tunnel Syndrome Patients	nan	COMPLETED
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS	nan	COMPLETED
Diagnosis of Carpal Tunnel Syndrome: Effectiveness of Diagnostic Tests. Clinical Trial of Accuracy	nan	COMPLETED
The Natural History of Alpha-Mannosidosis	nan	COMPLETED
Acute Pancreatitis Targets (APT) Study	nan	COMPLETED
Multi-omics Study in Citrin Deficiency	nan	ACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a CTSV binder may also engage these)

Protein	Name	Similarity
P06797	—	1.000	P06797 →
Q9GL24	—	1.000	Q9GL24 →
Q5E968	—	1.000	Q5E968 →
P25975	—	1.000	P25975 →
Q9GKL8	—	1.000	Q9GKL8 →
Q5E998	—	1.000	Q5E998 →
P55097	—	0.999	P55097 →
O35186	—	0.998	O35186 →
P25326	—	0.998	P25326 →
Q28944	—	0.997	Q28944 →
Q3ZKN1	—	0.997	Q3ZKN1 →
P61276	—	0.997	P61276 →
CTSS	Cathepsin S	0.997	landscape →
A0A1S4F2V5	—	0.996	A0A1S4F2V5 →
Q9GLE3	—	0.996	Q9GLE3 →
P61277	—	0.996	P61277 →
Q26636	—	0.995	Q26636 →
P25773	—	0.995	P25773 →
O70370	—	0.995	O70370 →
O45734	—	0.995	O45734 →
CTSK	Cathepsin K	0.995	landscape →
O65493	—	0.994	O65493 →
Q9JI81	—	0.994	Q9JI81 →
P43236	—	0.994	P43236 →
Q80UB0	—	0.993	Q80UB0 →
Q63088	—	0.993	Q63088 →
P07154	—	0.993	P07154 →
CTSL	Procathepsin L	0.993	landscape →
P12412	—	0.992	P12412 →
Q95029	—	0.992	Q95029 →