Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 16/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250095 | 0.81 | JAK2 (0.48) | JAK2THRBDHODH | |
| SCHEMBL11242987 | 0.81 | JAK2 (0.48) | JAK2THRBDHODH | |
| Water SCHEMBL11246907 | 0.80 | JAK2 (0.47) | JAK2THRBDHODH | |
| SCHEMBL1270735 | 0.77 | JAK2 (0.57) | JAK2THRBDHODHALDH1A1LMNA | |
| SCHEMBL1992586 | 0.70 | JAK2 (0.57) | JAK2THRBDHODHALDH1A1LMNA | |
| SCHEMBL2894307 | 0.70 | JAK2 (0.57) | JAK2THRBDHODHALDH1A1LMNA | |
| SCHEMBL22783664 | 0.70 | JAK2 (0.61) | JAK2THRBDHODHALDH1A1LMNA | |
| SCHEMBL25391975 | 0.67 | JAK2 (0.59) | JAK2THRBDHODHALDH1A1LMNA | |
| SCHEMBL10962665 | 0.67 | JAK2 (0.59) | JAK2THRBDHODHALDH1A1LMNA | |
| SCHEMBL9715507 | 0.66 | JAK2 (1.00) | JAK2THRBDHODHALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052341-A1 | Orotic acid derivatives and their use as agricultural chemicals | UBE INDUSTRIES, LTD. (JP) | 1982-05-26 | — | — | EP | claimed |