Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245615 | 0.85 | PTPN1 (0.44) | PTPN1PLA2G2DTRPV1MEN1KMT2A | |
| SCHEMBL11928334 | 0.80 | PLK1 (0.48) | — | |
| SCHEMBL27848610 | 0.78 | PTPN1 (0.55) | PTPN1PLA2G2DMEN1KMT2APOLB | |
| SCHEMBL7719495 | 0.77 | PLA2G2D (0.49) | PTPN1PLA2G2DTRPV1TTRMEN1 | |
| SCHEMBL688784 | 0.76 | PTPN1 (0.66) | PTPN1PLA2G2DTTRMEN1KMT2A | |
| SCHEMBL31357157 | 0.75 | PTPN1 (0.70) | PTPN1PLA2G2DTTRMEN1KMT2A | |
| SCHEMBL11400947 | 0.75 | MAOB (0.41) | TRPV1MEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL30290120 | 0.75 | P2RY14 (0.54) | PTPN1SLC6A2P2RY14 | |
| SCHEMBL22570620 | 0.75 | P2RY14 (0.54) | PTPN1SLC6A2P2RY14 | |
| SCHEMBL186327 | 0.74 | PTPN1 (0.68) | PTPN1PLA2G2DTTRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331613-A | Process for the preparation of trifluoromethylnaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |