SCHEMBL11245633

SCHEMBL11245633

CC1=CC(=N)C(Cl)=CC1=O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EEF2K O00418 1/20 0.37
PLK1 P53350 1/20 0.37
PLK2 Q9NYY3 1/20 0.37
STAT3 P40763 1/20 0.34
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11704367 0.77 PLK1 (0.46) EEF2KPLK1PLK2STAT3MEN1
SCHEMBL10786855 0.77 MEN1 (0.42) MEN1ALDH1A1MAPTHPGDALOX12
SCHEMBL2931396 0.77 EEF2K (0.46) EEF2KPLK1PLK2STAT3MEN1
P-Xyloquinone SCHEMBL49964 0.69 PLK1 (0.60) EEF2KPLK1PLK2STAT3MEN1
SCHEMBL7897027 0.69 ALDH1A1 (0.41) EEF2KPLK1PLK2STAT3MEN1
SCHEMBL4911549 0.63 MEN1 (0.47) MEN1ALDH1A1MAPTHPGDALOX12
SCHEMBL57290 0.63 MEN1 (0.56) MEN1ALDH1A1MAPTHPGDALOX12
SCHEMBL9011590 0.63
SCHEMBL1274862 0.62 MAPT (0.42) MEN1ALDH1A1MAPTHPGDALOX12
SCHEMBL11645496 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4361516-A N-Monosubstituted indoanilines SOCIETE ANONYME DITE: L'OREAL (FR) 1982-11-30 US disclosed