Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.81 |
| ▸ | HTT | P42858 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907417 | 0.90 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTLMNAALDH1A1TSHR | |
| SCHEMBL687206 | 0.88 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTLMNAALDH1A1TDP1 | |
| SCHEMBL31520571 | 0.88 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTLMNAALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL5344901 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2HTTLMNAALDH1A1TDP1 | |
| SCHEMBL618681 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2HTTLMNAALDH1A1TDP1 | |
| SCHEMBL8736878 | 0.83 | SMN1; SMN2 (0.85) | SMN1; SMN2HTTLMNAALDH1A1TDP1 | |
| SCHEMBL618590 | 0.83 | LMNA (0.85) | SMN1; SMN2HTTLMNAALDH1A1GAA | |
| SCHEMBL7009516 | 0.81 | SMN1; SMN2 (0.81) | SMN1; SMN2HTTLMNAALDH1A1GAA | |
| SCHEMBL28750635 | 0.81 | SMN1; SMN2 (0.81) | SMN1; SMN2HTTLMNAALDH1A1GAA | |
| SCHEMBL11237994 | 0.81 | CA12 (0.60) | SMN1; SMN2HTTLMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337274-A | Flukicidal compounds | BURROUGHS WELLCOME CO. (US) | 1982-06-29 | — | — | US | claimed |
| US-4337274-A | Flukicidal compounds | BURROUGHS WELLCOME CO. (US) | 1982-06-29 | — | — | US | disclosed |