Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642020 | 0.83 | MAPT (0.50) | POLBMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL17663794 | 0.82 | NPC1 (0.51) | POLBMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL6715920 | 0.81 | POLB (0.61) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2483519 | 0.80 | FPR2 (0.49) | POLBMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL2483521 | 0.80 | FPR2 (0.49) | POLBMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL146704 | 0.80 | FPR2 (0.49) | POLBMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL29274310 | 0.80 | MEN1 (0.60) | POLBMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL24833242 | 0.79 | POLB (0.58) | POLBMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL28534876 | 0.79 | FPR2 (0.47) | POLBMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9152364 | 0.77 | MAPT (0.46) | POLBMAPTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310429-A | HEAT AND OXIDATION RESISTANT AMINOACETAMIDES | THE B. F. GOODRICH COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| EP-0007182-A1 | Stabilized polymers, novel stabilizers and synthesis thereof | The B.F. GOODRICH Company (US) | 1980-01-23 | — | — | EP | disclosed |