Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709376 | 0.87 | USP5 (0.44) | USP5CYP2C9RXRARXRBSMN1; SMN2 | |
| SCHEMBL9246353 | 0.81 | CYP2C9 (0.44) | USP5CYP2C9RXRARXRBSMN1; SMN2 | |
| SCHEMBL28486290 | 0.79 | NPC1 (0.44) | SMN1; SMN2RAB9AALDH1A1L3MBTL1NPC1 | |
| SCHEMBL11078309 | 0.79 | CES1 (0.46) | SMN1; SMN2CYP2D6HIF1AALDH1A1POLB | |
| SCHEMBL25448181 | 0.77 | CYP2C9 (0.41) | USP5CYP2C9RXRARXRBSMN1; SMN2 | |
| SCHEMBL12632153 | 0.76 | CYP2C9 (0.50) | USP5CYP2C9RXRARXRBSMN1; SMN2 | |
| SCHEMBL22660971 | 0.76 | USP5 (0.46) | USP5CYP2C9RXRARXRBSMN1; SMN2 | |
| SCHEMBL54909 | 0.74 | CYP2C9 (0.50) | USP5CYP2C9RXRARXRBSMN1; SMN2 | |
| SCHEMBL4453109 | 0.74 | USP5 (0.47) | USP5CYP2C9RXRARXRBSMN1; SMN2 | |
| SCHEMBL9819157 | 0.73 | CYP2C9 (0.38) | USP5CYP2C9RXRARXRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321118-A | Bis benzoyl sensitizers for photopolymerization or photo cross linking process and composition | CIBA-GEIGY CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4318791-A | PHOTOPOLYMERIZABLE SYSTEM FOR INKS | CIBA-GEIGY CORPORATION (US) | 1982-03-09 | — | — | US | disclosed |
| US-4315807-A | Sensitizers for photopolymerization | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| US-4308400-A | AROMATIC HYDROXY KETONES | CIBA-GEIGY A.G. (CH) | 1981-12-29 | — | — | US | disclosed |