Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246353 | 0.81 | CYP2C9 (0.44) | CYP2C9USP5CYP2D6HIF1AL3MBTL1 | |
| SCHEMBL9819157 | 0.80 | CYP2C9 (0.38) | CYP2C9USP5CYP2D6HIF1AL3MBTL1 | |
| SCHEMBL3794690 | 0.77 | CYP2C9 (0.36) | CYP2C9USP5CYP2D6HIF1AL3MBTL1 | |
| SCHEMBL11245870 | 0.77 | USP5 (0.44) | CYP2C9USP5CYP2D6HIF1AL3MBTL1 | |
| SCHEMBL10709376 | 0.77 | USP5 (0.44) | CYP2C9USP5CYP2D6HIF1AL3MBTL1 | |
| SCHEMBL12632153 | 0.76 | CYP2C9 (0.50) | CYP2C9USP5CYP2D6HIF1ASMN1; SMN2 | |
| SCHEMBL23489040 | 0.76 | CYP2C9 (0.49) | CYP2C9USP5CYP2D6HIF1AL3MBTL1 | |
| SCHEMBL54909 | 0.74 | CYP2C9 (0.50) | CYP2C9USP5CYP2D6HIF1ASMN1; SMN2 | |
| SCHEMBL10942936 | 0.74 | CYP2C9 (0.46) | CYP2C9USP5CYP2D6HIF1ASMN1; SMN2 | |
| SCHEMBL10752558 | 0.73 | CYP2C9 (0.47) | CYP2C9USP5CYP2D6HIF1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230141981-A1 | NOVEL COMPOUNDS AND COMPOSITION FOR TARGETED THERAPY OF KIDNEY-ASSOCIATED CANCERS | Shanghai MICURX Pharmaceuticals Co., Ltd. (CN) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230141981-A1 | NOVEL COMPOUNDS AND COMPOSITION FOR TARGETED THERAPY OF KIDNEY-ASSOCIATED CANCERS | GLS, ATP6V1B1, KRAS | CYP2C9 4256/4885USP5 3499/4885ELANE 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.