Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.64 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.63 |
| ▸ | PLK1 | P53350 | 3/20 | 0.60 |
| ▸ | RARB | P10826 | 3/20 | 0.60 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705230 | 1.00 | THRA (0.66) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL7171001 | 1.00 | THRA (0.66) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL10944158 | 1.00 | THRA (0.66) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL15153314 | 1.00 | THRA (0.66) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL1988903 | 0.98 | THRA (0.64) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL1023516 | 0.95 | THRA (0.59) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL2341095 | 0.89 | KMT2A (0.55) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL7167821 | 0.88 | THRA (0.54) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL7167816 | 0.88 | THRA (0.54) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL11706058 | 0.88 | THRA (0.66) | THRATHRBTP53TSHRPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342875-A | STABILIZERS FOR OLEFIN POLYMERS | CINCINNATI-MILACRON, INC. (US) | 1982-08-03 | — | — | US | disclosed |