Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.56 |
| ▸ | EP300 | Q09472 | 2/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12235264 | 0.89 | TDP1 (0.48) | IDO1KDM4EHTTTDP1ALDH1A1 | |
| SCHEMBL3588877 | 0.87 | IDO1 (0.44) | IDO1EP300KAT2BKAT8HDAC3 | |
| SCHEMBL4612497 | 0.84 | IDO1 (0.65) | IDO1EP300KAT2BKAT8HDAC3 | |
| SCHEMBL17537713 | 0.84 | TDP1 (0.44) | KDM4EGAANPC1LMNAHTT | |
| SCHEMBL11742202 | 0.81 | IDO1 (0.54) | IDO1EP300KAT2BKAT8HDAC3 | |
| SCHEMBL11741406 | 0.81 | IDO1 (0.54) | IDO1EP300KAT2BKAT8HDAC3 | |
| SCHEMBL1467932 | 0.81 | TAAR1 (0.57) | IDO1EP300KAT2BKAT8HDAC3 | |
| SCHEMBL17537711 | 0.80 | POLB (0.45) | KDM4EGAAHTTTDP1ALDH1A1 | |
| SCHEMBL1397170 | 0.79 | IDO1 (0.65) | IDO1EP300KAT2BKAT8HDAC3 | |
| SCHEMBL29357437 | 0.79 | IDO1 (0.65) | IDO1EP300KAT2BKAT8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362795-A | CONTAINING A 4-ALKOXY-1-NAPHTHOL; X-RAY FILM | FUJI PHOTO FILM CO., LTD. (JP) | 1982-12-07 | — | — | US | claimed |
| US-4042635-A | Spiro compounds | CIBA-GEIGY CORPORATION (US) | 1977-08-16 | — | — | US | disclosed |
| US-3950403-A | Spiro compounds | CIBA-GEIGY CORPORATION (US) | 1976-04-13 | — | — | US | disclosed |