Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | GCGR | P47871 | 2/20 | 0.60 |
| ▸ | PNLIP | P16233 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | PYGL | P06737 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.45 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242062 | 0.92 | TDP1 (0.67) | TDP1GCGRPNLIPMRGPRX4PYGL | |
| SCHEMBL11237966 | 0.92 | TDP1 (0.67) | TDP1GCGRPNLIPMRGPRX4PYGL | |
| SCHEMBL11241126 | 0.89 | TDP1 (0.81) | TDP1GCGRPYGLNPC1POLB | |
| SCHEMBL11237411 | 0.87 | GCGR (0.71) | TDP1GCGRPNLIPMRGPRX4PYGL | |
| SCHEMBL11245808 | 0.87 | GCGR (0.64) | TDP1GCGRPNLIPPYGLNPC1 | |
| SCHEMBL10632426 | 0.86 | TDP1 (0.76) | TDP1GCGRPNLIPPYGLNPC1 | |
| SCHEMBL11233072 | 0.86 | MRGPRX4 (0.53) | TDP1GCGRPNLIPMRGPRX4NPC1 | |
| Triflumuron SCHEMBL23700 | 0.84 | TDP1 (1.00) | TDP1GCGRNPC1POLBPKM | |
| Triflumuron SCHEMBL9490691 | 0.84 | TDP1 (1.00) | TDP1GCGRNPC1POLBPKM | |
| Triflumuron SCHEMBL29832813 | 0.84 | TDP1 (1.00) | TDP1GCGRNPC1POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |