Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11169336 | 0.82 | LMNA (0.58) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11391498 | 0.80 | LMNA (0.63) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL10969896 | 0.79 | LMNA (0.61) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL10971142 | 0.79 | MAPT (0.64) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL15698920 | 0.78 | MAPT (0.57) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL10972574 | 0.73 | LMNA (0.55) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL1031488 | 0.73 | LMNA (0.71) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL11393449 | 0.72 | MAPT (0.54) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL31305767 | 0.72 | LMNA (0.69) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL31305775 | 0.72 | LMNA (0.69) | MAPTLMNAMAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348519-A | ANTIINFLAMMATORY, ANALGESIC, ANTIRHEUMATIC, ANTITHROMBOTIC | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |