Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258464 | 0.82 | CACNA1C (0.36) | MAPK1ALDH1A1KDM4ELMNA | |
| SCHEMBL11257844 | 0.81 | CACNA1C (0.47) | MAPK1HTTALDH1A1KDM4EPOLB | |
| SCHEMBL11258362 | 0.79 | HTT (0.42) | MAPK1HTTALDH1A1KDM4EPOLB | |
| SCHEMBL11050902 | 0.79 | MAPK1 (0.49) | MAPK1HTTALDH1A1KDM4EPOLB | |
| SCHEMBL11417226 | 0.78 | POLB (0.40) | HTTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11053827 | 0.77 | MAPK1 (0.54) | MAPK1HTTPOLBMEN1KMT2A | |
| SCHEMBL11252413 | 0.77 | POLB (0.51) | HTTALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL11255736 | 0.75 | HTT (0.41) | MAPK1HTTALDH1A1KDM4EPOLB | |
| SCHEMBL11049761 | 0.74 | MAPK1 (0.48) | MAPK1HTTALDH1A1KDM4EPOLB | |
| SCHEMBL11056677 | 0.74 | HTT (0.46) | MAPK1HTTALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |