Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251144 | 0.89 | CYP19A1 (0.47) | CYP19A1KCNN4CYP3A4CYP3A5HTR2A | |
| SCHEMBL11247324 | 0.86 | CYP19A1 (0.35) | CYP19A1KCNN4CYP3A4CYP3A5HTR2A | |
| SCHEMBL11250000 | 0.78 | MEN1 (0.41) | CYP19A1CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL9669413 | 0.78 | KCNN4 (0.52) | CYP19A1KCNN4CYP3A4CYP3A5HTR2A | |
| SCHEMBL11239589 | 0.75 | CYP3A4 (0.46) | CYP19A1KCNN4CYP3A4CYP3A5HTR2A | |
| SCHEMBL487445 | 0.75 | KCNN4 (0.48) | CYP19A1KCNN4CYP3A4CYP3A5HTR2A | |
| SCHEMBL11256928 | 0.73 | TSHR (0.43) | CYP19A1CYP3A4CYP3A5MEN1KMT2A | |
| SCHEMBL11248026 | 0.73 | CYP19A1 (0.47) | CYP19A1KCNN4CYP3A4CYP3A5HTR2A | |
| SCHEMBL9067519 | 0.71 | KCNN4 (0.52) | CYP19A1KCNN4CYP3A4CYP3A5HTR2A | |
| SCHEMBL11871226 | 0.71 | KCNN4 (0.42) | CYP19A1KCNN4CYP3A4CYP3A5HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322442-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |