Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247324 | 0.88 | CYP19A1 (0.35) | CYP19A1CYP3A4CYP3A5MEN1KMT2A | |
| SCHEMBL11251144 | 0.84 | CYP19A1 (0.47) | CYP19A1CYP3A4CYP3A5MEN1KMT2A | |
| SCHEMBL11261677 | 0.84 | TSHR (0.43) | CYP19A1CYP3A4CYP3A5MEN1KMT2A | |
| SCHEMBL11245253 | 0.83 | CYP3A4 (0.46) | CYP19A1CYP3A4CYP3A5MEN1KMT2A | |
| SCHEMBL11258472 | 0.82 | MEN1 (0.46) | CYP19A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL9669413 | 0.79 | KCNN4 (0.52) | CYP19A1CYP3A4CYP3A5MEN1KMT2A | |
| SCHEMBL487445 | 0.76 | KCNN4 (0.48) | CYP19A1CYP3A4CYP3A5MEN1KMT2A | |
| SCHEMBL11242169 | 0.75 | MEN1 (0.39) | CYP19A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL11258403 | 0.74 | CYP19A1 (0.50) | CYP19A1CYP3A4CYP3A5MEN1KMT2A | |
| SCHEMBL11249211 | 0.74 | CYP19A1 (0.40) | CYP19A1CYP3A4CYP3A5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322442-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |