Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.81 |
| ▸ | NPC1 | O15118 | 7/20 | 0.74 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.70 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.70 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | F10 | P00742 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798428 | 0.91 | MEN1 (0.83) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29808279 | 0.91 | MEN1 (0.83) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL12077495 | 0.91 | MEN1 (0.83) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5928817 | 0.88 | TSHR (0.80) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21829023 | 0.88 | KMT2A (0.78) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14075227 | 0.88 | MEN1 (0.78) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28397053 | 0.88 | KMT2A (0.78) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29278946 | 0.87 | MEN1 (0.76) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL882567 | 0.87 | MEN1 (0.76) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5226157 | 0.85 | NPC1 (1.00) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342875-A | STABILIZERS FOR OLEFIN POLYMERS | CINCINNATI-MILACRON, INC. (US) | 1982-08-03 | — | — | US | disclosed |