Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | RAB9A | P51151 | 6/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.68 |
| ▸ | PYGM | P11217 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.63 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.63 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246385 | 0.91 | MEN1 (1.00) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL12077495 | 0.85 | MEN1 (0.83) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29808279 | 0.85 | MEN1 (0.83) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28241911 | 0.85 | MEN1 (0.74) | MEN1KMT2ARAB9ASIRT2NPC1 | |
| SCHEMBL27696853 | 0.85 | PYGM (0.78) | MEN1KMT2ARAB9ASMN1; SMN2PYGM | |
| SCHEMBL16681360 | 0.84 | KMT2A (0.76) | MEN1KMT2ARAB9ASIRT2NPC1 | |
| SCHEMBL527994 | 0.84 | RAB9A (0.77) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL29989592 | 0.84 | RAB9A (0.77) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL8970331 | 0.84 | MAPT (0.65) | MEN1KMT2ARAB9ASIRT2NPC1 | |
| SCHEMBL4651232 | 0.83 | MEN1 (0.66) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |