Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258889 | 0.88 | GAA (0.51) | TSHRCYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL11267080 | 0.88 | GAA (0.51) | TSHRCYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL11255918 | 0.88 | GAA (0.51) | TSHRCYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL11255623 | 0.88 | GAA (0.51) | TSHRCYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL11125775 | 0.87 | GAA (0.50) | TSHRCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL11259085 | 0.84 | MEN1 (0.43) | TSHRGAA | |
| SCHEMBL9432758 | 0.81 | ITGB3 (0.47) | GAA | |
| SCHEMBL11256526 | 0.76 | PDE4A (0.41) | TSHRCYP1A2CYP2C19GAA | |
| SCHEMBL11268890 | 0.75 | FFAR1 (0.41) | GAAPTGER4PTGER2 | |
| SCHEMBL7352920 | 0.74 | ATM (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330550-A | ANTICOAGULANTS AND ANALGESICS | A. NATTERMANN & CIE. GMBH (DE) | 1982-05-18 | — | — | US | claimed |