Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238324 | 0.89 | CYP11B1 (0.55) | CYP11B1CYP11B2KMT2AMEN1HMOX1 | |
| SCHEMBL11241708 | 0.88 | CYP11B1 (0.49) | CYP11B1CYP11B2KMT2AMEN1KDM4E | |
| SCHEMBL11229057 | 0.88 | CYP11B1 (0.49) | CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11230104 | 0.88 | CYP11B1 (0.49) | CYP11B1CYP11B2KMT2AMEN1HMOX1 | |
| SCHEMBL11249818 | 0.88 | CYP11B1 (0.39) | CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11233705 | 0.86 | CYP11B1 (0.52) | CYP11B1CYP11B2KMT2AMEN1HMOX1 | |
| SCHEMBL11239251 | 0.86 | CYP11B1 (0.50) | CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11237327 | 0.86 | CYP11B1 (0.47) | CYP11B1CYP11B2KMT2AHMOX1 | |
| SCHEMBL11247213 | 0.86 | CYP11B1 (0.48) | CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11235854 | 0.86 | CYP11B1 (0.40) | CYP11B1CYP11B2HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |