Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28998207 | 0.80 | TDP1 (0.46) | EGFRTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL28455625 | 0.78 | EGFR (0.37) | EGFRTDP1ALDH1A1PDE4APDE4B | |
| SCHEMBL4905093 | 0.77 | ALDH1A1 (0.58) | EGFRPOLBGPR35TDP1ALDH1A1 | |
| SCHEMBL26616688 | 0.77 | ALDH1A1 (0.44) | EGFRPOLBGPR35TDP1ALDH1A1 | |
| SCHEMBL3107938 | 0.74 | ALDH1A1 (0.49) | EGFRPOLBTDP1ALDH1A1MEN1 | |
| SCHEMBL26006397 | 0.74 | MERTK (0.38) | EGFRTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL2098010 | 0.73 | ALDH1A1 (0.62) | POLBGPR35TDP1ALDH1A1MEN1 | |
| SCHEMBL6634280 | 0.73 | PDE10A (0.51) | POLBGPR35TDP1ALDH1A1MEN1 | |
| SCHEMBL8856272 | 0.73 | TSHR (0.45) | EGFRPOLBTDP1ALDH1A1MEN1 | |
| SCHEMBL8808732 | 0.72 | PDE4A (0.52) | EGFRTDP1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |