Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791495 | 0.85 | GAA (0.58) | SMN1; SMN2GAAPOLBLMNAMAPT | |
| SCHEMBL23182885 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2NOX1GAAPOLBLMNA | |
| SCHEMBL11251960 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2NOX1GAAPOLBLMNA | |
| SCHEMBL18622660 | 0.83 | FERMT2 (0.50) | SMN1; SMN2NOX1GAAPOLBMAPT | |
| SCHEMBL7531364 | 0.82 | LMNA (0.58) | SMN1; SMN2GAAPOLBLMNAMAPT | |
| SCHEMBL7650131 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2NOX1GAAPOLBEGFR | |
| SCHEMBL7655772 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2NOX1GAAPOLBLMNA | |
| SCHEMBL7655919 | 0.80 | FERMT2 (0.52) | SMN1; SMN2NOX1GAAMAPTHTT | |
| SCHEMBL7655830 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2NOX1GAAPOLBLMNA | |
| SCHEMBL11333572 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2GAALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3735411-B1 | 1,3,4,5-TETRAHYDRO-2H-PYRIDO[4,3-B]INDOLE DERIVATIVES FOR THE TREATMENT, ALLEVIATION OR PREVENTION OF DISORDERS ASSOCIATED WITH TAU AGGREGATES LIKE ALZHEIMER`S DISEASE | AC IMMUNE SA (CH) | 2024-07-10 | — | — | EP | disclosed |
| EP-2308872-A1 | Heterocyclic derivatives as modulators of ion channels | Vertex Pharmaceuticals Incorporated (US) | 2011-04-13 | — | — | EP | disclosed |
| US-4360465-A | PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |
| EP-0017946-B1 | SALTS OF ALPHA-AMINOACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT GROWTH REGULATORS | BASF Aktiengesellschaft (DE) | 1982-04-14 | — | — | EP | disclosed |
| EP-0017946-A1 | Salts of alpha-aminoacetanilides, process for their preparation and their use as plant growth regulators | BASF Aktiengesellschaft (DE) | 1980-10-29 | — | — | EP | disclosed |