Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291779 | 0.69 | GPR3 (0.40) | GPR3MAPTRAB9AMEN1KMT2A | |
| SCHEMBL278665 | 0.68 | GPR3 (0.43) | GPR3MAPTRAB9AMEN1KMT2A | |
| SCHEMBL30875499 | 0.66 | GPR3 (0.40) | GPR3MAPTRAB9AMEN1KMT2A | |
| SCHEMBL17675486 | 0.66 | GPR3 (0.40) | GPR3MAPTRAB9AMEN1KMT2A | |
| SCHEMBL6545120 | 0.63 | GPR3 (0.52) | GPR3MAPTRAB9AMEN1KMT2A | |
| SCHEMBL10671329 | 0.63 | LIMK1 (0.43) | GPR3MAPTRAB9AMEN1KMT2A | |
| Dibenzothiophene SCHEMBL13294 | 0.62 | GPR3 (1.00) | GPR3MAPTRAB9AMEN1KMT2A | |
| Dibenzothiophene SCHEMBL30167635 | 0.62 | GPR3 (1.00) | GPR3MAPTRAB9AMEN1KMT2A | |
| Dibenzothiophene SCHEMBL14659543 | 0.62 | GPR3 (1.00) | GPR3MAPTRAB9AMEN1KMT2A | |
| SCHEMBL12228803 | 0.60 | GPR3 (0.55) | GPR3MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007649-A | Targeted synergistic cancer immunotherapy | 布里格姆及妇女医院股份有限公司 | 2022-02-01 | — | — | CN | claimed |
| EP-3575791-B1 | BLOOD TREATMENT METHOD AND BLOOD COLLECTION TUBE | ARKRAY INC (JP) | 2024-01-10 | — | — | EP | disclosed |
| CN-114007649-A | Targeted synergistic cancer immunotherapy | 布里格姆及妇女医院股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| EP-3575791-A1 | BLOOD TREATMENT METHOD AND BLOOD COLLECTION TUBE | ARKRAY, Inc. (JP) | 2019-12-04 | — | — | EP | disclosed |
| US-4348519-A | ANTIINFLAMMATORY, ANALGESIC, ANTIRHEUMATIC, ANTITHROMBOTIC | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0021058-A3 | DERIVATIVES OF BENZOTHIENOTHIAZINE, THEIR USE, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-01-28 | — | — | EP | disclosed |
| EP-0021058-A2 | Derivatives of benzothienothiazine, their use, process and intermediates for their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-01-07 | — | — | EP | disclosed |
| EP-0021058-A2 | Derivatives of benzothienothiazine, their use, process and intermediates for their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-01-07 | — | — | EP | disclosed |