SCHEMBL11247629

SCHEMBL11247629

N#CCC1(O)CCSCC1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.30
JAK1 P23458 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11245376 0.77
SCHEMBL11371451 0.75 ALDH1A1 (0.46)
SCHEMBL11253304 0.75 ALDH1A1 (0.46)
SCHEMBL7759366 0.75 ALDH1A1 (0.46)
SCHEMBL23119937 0.73 ALDH1A1 (0.30)
SCHEMBL16486380 0.73
SCHEMBL11250288 0.71
Hydrochloric Acid SCHEMBL18693002 0.70 POLB (0.34)
SCHEMBL22911098 0.69
SCHEMBL927779 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0001900-B1 9-THIA-12-AZAPROSTANOIC ACID DERIVATIVES AND COMPOSITIONS CONTAINING THEM MERCK & CO. INC. (US) 1982-04-07 EP disclosed
US-4225609-A Interphenylene 9-thia-11-oxo-12-aza-prostanoic acids MERCK & CO., INC. (US) 1980-09-30 US disclosed
EP-0001900-A1 9-Thia-12-azaprostanoic acid derivatives and compositions containing them MERCK & CO. INC. (US) 1979-05-16 EP disclosed