Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12500219 | 0.91 | KDM4E (0.71) | KDM4EGLAL3MBTL1HPGDGAA | |
| Phenylacetic Acid SCHEMBL1835502 | 0.84 | AKR1B1 (0.59) | KDM4EGLAL3MBTL1HPGDGAA | |
| Phenylacetic Acid SCHEMBL5550380 | 0.81 | KDM4E (0.56) | KDM4EL3MBTL1GAALMNAMAPK8 | |
| SCHEMBL31662771 | 0.79 | LMNA (0.64) | KDM4EL3MBTL1LMNANPC1KMT2A | |
| SCHEMBL11111266 | 0.79 | GAA (0.62) | L3MBTL1HPGDGAALMNAATM | |
| SCHEMBL5550382 | 0.79 | KDM4E (0.47) | KDM4EGLAL3MBTL1HPGDLMNA | |
| Bromide SCHEMBL11105861 | 0.78 | GAA (0.60) | L3MBTL1HPGDGAALMNAATM | |
| Hydrochloric Acid SCHEMBL11105183 | 0.78 | GAA (0.60) | L3MBTL1HPGDGAALMNAATM | |
| SCHEMBL16384277 | 0.77 | CYP3A4 (0.63) | KDM4EHPGDGAALMNANPC1 | |
| SCHEMBL15229237 | 0.77 | NPC1 (0.59) | KDM4EL3MBTL1HPGDGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314079-A | Novel methoxyethylamine | AMERICAN CYANAMID COMPANY (US) | 1982-02-02 | — | — | US | claimed |
| EP-0010851-A2 | Process for the preparation of tetramisole | AMERICAN CYANAMID COMPANY (US) | 1980-05-14 | — | — | EP | claimed |