SCHEMBL11247675

SCHEMBL11247675

N#Cc1cn(-c2ccc(F)cc2F)c(=O)[nH]c1=O

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.48
KMT2A Q03164 4/20 0.47
MEN1 O00255 2/20 0.47
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.39
BCAT2 O15382 4/20 0.33
BCAT1 P54687 4/20 0.33
PGR P06401 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11241468 0.86 L3MBTL1 (0.46) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11246109 0.86 GAA (0.50) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11251632 0.86 GAA (0.50) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL8888395 0.86 L3MBTL1 (0.46) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11246681 0.84 L3MBTL1 (0.47) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11242927 0.83 GAA (0.51) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11246044 0.81 GAA (0.47) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11237480 0.80 L3MBTL1 (0.68) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11253559 0.78 L3MBTL1 (0.54) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11253309 0.76 L3MBTL1 (0.49) L3MBTL1KMT2AMEN1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358591-A BACTERICIDES, FUNGICIDES; PLANT DISEASES ZOECON CORPORATION (US) 1982-11-09 US disclosed
US-4338318-A FUNGICIDE OR BACERICIDE TO TREAT PLANT DISEASES WITH A PHENYL URACIL ZOECON CORPORATION (US) 1982-07-06 US disclosed
US-4307098-A 2-PHENYL-URACIL COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-12-22 US disclosed
US-4297297-A α-Cyano-β-(substituted-anilino)-N-ethoxycarbonylacrylamide intermediates ZOECON CORP. (US) 1981-10-27 US disclosed
US-4266056-A FUNGICIDES, BACTERICIDES ZOECON CORPORATION (US) 1981-05-05 US disclosed