Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10407017 | 0.94 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL221075 | 0.94 | — | — | |
| Bicarbonate SCHEMBL9752344 | 0.94 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL743552 | 0.94 | — | — | |
| Bicarbonate SCHEMBL18127937 | 0.88 | CA1 (0.62) | — | |
| Bicarbonate SCHEMBL20639275 | 0.88 | — | — | |
| Bicarbonate SCHEMBL28213677 | 0.88 | — | — | |
| Bicarbonate SCHEMBL8521119 | 0.88 | — | — | |
| Bicarbonate SCHEMBL5708433 | 0.88 | CA1 (0.62) | — | |
| Bicarbonate SCHEMBL5720560 | 0.88 | CA1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331706-A | Composite zinc oxide coating on an inert pigment core product and process | THE SHERWIN-WILLIAMS COMPANY (US) | 1982-05-25 | — | — | US | disclosed |
| US-4207377-A | PHOTOREPRODUCTIVE COATING COMPOSITION AND COPY PAPER | THE SHERWIN-WILLIAMS COMPANY (US) | 1980-06-10 | — | — | US | disclosed |