Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | LDHA | P00338 | 2/20 | 0.46 |
| ▸ | LDHB | P07195 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL221075 | 1.00 | — | — | |
| Bicarbonate SCHEMBL743552 | 1.00 | — | — | |
| Bicarbonate SCHEMBL10407017 | 1.00 | CA1 (0.71) | CA1CA2CA9ACHELDHA | |
| Bicarbonate SCHEMBL11247758 | 0.94 | — | — | |
| Bicarbonate SCHEMBL18127937 | 0.94 | CA1 (0.62) | CA1CA2CA9ACHELDHA | |
| Bicarbonate SCHEMBL8521119 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28168051 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5720560 | 0.94 | CA1 (0.62) | CA1CA2CA9ACHELDHA | |
| Bicarbonate SCHEMBL20639275 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5708433 | 0.94 | CA1 (0.62) | CA1CA2CA9ACHELDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387844-B | Preparation method of dialkyl azodicarbonate | 浙江瑞博制药有限公司 | 2024-03-12 | — | — | CN | claimed |
| WO-1991000724-A1 | ALKYNYL AMINES THAT REGULATE CHOLINERGIC NEUROTRANSMISSION | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | disclosed |