Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16979030 | 0.82 | SLC6A4 (0.49) | SLC6A4IDO1SLC6A2SLC6A3FPR2 | |
| SCHEMBL4598274 | 0.80 | SLC6A4 (0.47) | SLC6A4IDO1SLC6A2FPR2PROKR1 | |
| SCHEMBL744402 | 0.80 | SLC6A4 (0.47) | SLC6A4IDO1SLC6A2SLC6A3FPR2 | |
| SCHEMBL19144912 | 0.79 | IDO1 (0.64) | SLC6A4IDO1SLC6A2SLC6A3FPR2 | |
| Iodide SCHEMBL744206 | 0.78 | SLC6A4 (0.46) | SLC6A4IDO1SLC6A2SLC6A3FPR2 | |
| SCHEMBL3137822 | 0.77 | EPHX1 (0.53) | SLC6A4IDO1SLC6A2FPR2PROKR1 | |
| SCHEMBL18253202 | 0.77 | SLC6A4 (0.45) | SLC6A4IDO1SLC6A2LMNAFPR2 | |
| SCHEMBL6347241 | 0.76 | SLC6A4 (0.43) | SLC6A4IDO1SLC6A2SLC6A3FPR2 | |
| SCHEMBL18306246 | 0.76 | IDO1 (0.59) | ESR1ESR2IDO1OPRM1CYP3A4 | |
| SCHEMBL28337671 | 0.72 | ESR1 (0.52) | SLC6A4ESR1PDCD1ESR2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311708-A | ADRENERGIC BLOCKING AGENTS | SYNTHELABO (FR) | 1982-01-19 | — | — | US | disclosed |
| US-4252984-A | 1-/P-/2-/CYCLOPROPYLMETHOXY/ETHYL/PHENOXY/-3-ISOPROPYLAMINO-2 -PROPANOL | SYNTHELABO (FR) | 1981-02-24 | — | — | US | disclosed |