Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16979030 | 0.82 | SLC6A4 (0.49) | SLC6A4IDO1SLC6A2PPARGPPARD | |
| SCHEMBL744402 | 0.80 | SLC6A4 (0.47) | SLC6A4IDO1SLC6A2FPR2PROKR1 | |
| SCHEMBL11248115 | 0.80 | SLC6A4 (0.47) | SLC6A4IDO1SLC6A2FPR2PROKR1 | |
| SCHEMBL19144912 | 0.79 | IDO1 (0.64) | SLC6A4IDO1SLC6A2FPR2PROKR1 | |
| Iodide SCHEMBL744206 | 0.78 | SLC6A4 (0.46) | SLC6A4IDO1SLC6A2FPR2PROKR1 | |
| SCHEMBL3137822 | 0.77 | EPHX1 (0.53) | SLC6A4IDO1SLC6A2FPR2PROKR1 | |
| SCHEMBL18253202 | 0.77 | SLC6A4 (0.45) | SLC6A4IDO1SLC6A2FPR2PROKR1 | |
| SCHEMBL2761538 | 0.77 | IDO1 (0.36) | IDO1FPR2PROKR1POLB | |
| SCHEMBL6347241 | 0.76 | SLC6A4 (0.43) | SLC6A4IDO1SLC6A2FPR2PROKR1 | |
| SCHEMBL14992303 | 0.73 | CHRNB2 (0.34) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908471-A1 | Tetrahydropyridines as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |