SCHEMBL11248237

SCHEMBL11248237

Cc1cccc(O[C@@H]2CCN(C)CC[C@H]2O)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSV O60911 2/20 0.50
CTSL P07711 2/20 0.50
CTSB P07858 2/20 0.50
CTSS P25774 2/20 0.50
CTSK P43235 2/20 0.50
CTSC P53634 2/20 0.50
CTSF Q9UBX1 2/20 0.50
CTSH P09668 1/20 0.50
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
GBA1 P04062 2/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP2D6 P10635 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
SSTR1 P30872 1/20 0.37
SSTR4 P31391 1/20 0.37
ATM Q13315 1/20 0.36
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11248230 1.00 CTSV (0.50) CTSVCTSLCTSBCTSSCTSK
SCHEMBL11248234 1.00 CTSV (0.50) CTSVCTSLCTSBCTSSCTSK
SCHEMBL11241271 0.90 CTSV (0.52) CTSVCTSLCTSBCTSSCTSK
SCHEMBL11237384 0.90 CTSV (0.52) CTSVCTSLCTSBCTSSCTSK
SCHEMBL11237393 0.90 CTSV (0.52) CTSVCTSLCTSBCTSSCTSK
SCHEMBL11237386 0.90 CTSV (0.52) CTSVCTSLCTSBCTSSCTSK
SCHEMBL11241262 0.90 CTSV (0.52) CTSVCTSLCTSBCTSSCTSK
SCHEMBL11248790 0.84 CTSV (0.49) CTSVCTSLCTSBCTSSCTSK
SCHEMBL11240615 0.84 CTSV (0.49) CTSVCTSLCTSBCTSSCTSK
SCHEMBL11248786 0.84 CTSV (0.49) CTSVCTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4320137-A Derivatives of perhydro-aza-heterocycles CIBA-GEIGY CORPORATION (US) 1982-03-16 US disclosed
US-4246269-A Antidepressant piperidinones CIBA-GEIGY CORPORATION (US) 1981-01-20 US disclosed
US-4160837-A ANTIDEPRESSANTS CIBA-GEIGY CORPORATION (US) 1979-07-10 US disclosed