Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.61 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.61 |
| ▸ | ALB | P02768 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246339 | 0.90 | MAPT (0.65) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11010391 | 0.88 | NR1I2 (0.76) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11375976 | 0.87 | MAPT (0.65) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11372310 | 0.86 | MAPT (0.65) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL10676259 | 0.86 | NR1I2 (0.67) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11796575 | 0.86 | NR1I2 (0.76) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11252200 | 0.85 | MAPT (0.64) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL8973257 | 0.85 | MAPT (0.80) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL8973246 | 0.85 | MAPT (0.80) | TDP1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL6693576 | 0.85 | MAPT (0.80) | TDP1MAPTNR1I2SLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006146-B1 | CEPHEM DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-09-15 | — | — | EP | disclosed |
| US-4282220-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | disclosed |
| EP-0006146-A1 | Cephem derivatives, process for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-09 | — | — | EP | disclosed |