Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.48 |
| ▸ | SOD1 | P00441 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247856 | 0.95 | CYP19A1 (0.46) | CYP19A1SOD1TBXAS1POLBGSK3B | |
| SCHEMBL11253669 | 0.89 | CYP19A1 (0.44) | CYP19A1SOD1TBXAS1POLBGSK3B | |
| SCHEMBL11353545 | 0.88 | CYP19A1 (0.50) | CYP19A1SOD1POLBCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL9996057 | 0.86 | CYP19A1 (0.49) | CYP19A1SOD1POLBCYP11B1CYP11B2 | |
| SCHEMBL11261411 | 0.86 | CYP19A1 (0.40) | CYP19A1SOD1TBXAS1POLB | |
| SCHEMBL11241264 | 0.84 | CYP11B1 (0.49) | CYP19A1TBXAS1POLBQPCTCYP11B1 | |
| SCHEMBL11257861 | 0.83 | HMOX1 (0.43) | CYP19A1SOD1TBXAS1POLB | |
| SCHEMBL11259562 | 0.83 | CYP19A1 (0.46) | CYP19A1SOD1TBXAS1POLBGSK3B | |
| SCHEMBL11356373 | 0.83 | CYP19A1 (0.48) | CYP19A1SOD1TBXAS1POLBCYP11B1 | |
| Hydrochloric Acid SCHEMBL11356376 | 0.82 | CYP19A1 (0.47) | CYP19A1SOD1TBXAS1POLBCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015750-B1 | 1-(NAPHTHYL-N-PROPYL)IMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, METHODS OF MAKING THEM AND THEIR USE FOR PHARMACEUTICALS | SYNTEX (U.S.A.) INC. (US) | 1982-11-24 | — | — | EP | claimed |
| US-4293561-A | ANTICONVULSANT ANTISECRETORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1981-10-06 | — | — | US | claimed |
| EP-0015750-A1 | 1-(Naphthyl-n-propyl)imidazole derivatives, compositions containing them, methods of making them and their use for pharmaceuticals | SYNTEX (U.S.A.) INC. (US) | 1980-09-17 | — | — | EP | claimed |
| EP-0015750-B1 | 1-(NAPHTHYL-N-PROPYL)IMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, METHODS OF MAKING THEM AND THEIR USE FOR PHARMACEUTICALS | SYNTEX (U.S.A.) INC. (US) | 1982-11-24 | — | — | EP | disclosed |
| US-4293561-A | ANTICONVULSANT ANTISECRETORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1981-10-06 | — | — | US | disclosed |
| EP-0015750-A1 | 1-(Naphthyl-n-propyl)imidazole derivatives, compositions containing them, methods of making them and their use for pharmaceuticals | SYNTEX (U.S.A.) INC. (US) | 1980-09-17 | — | — | EP | disclosed |