Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 3/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.49 |
| ▸ | NT5E | P21589 | 2/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | HINT1 | P49773 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242728 | 1.00 | P2RY6 (0.49) | P2RY6P2RY14NT5ETYMSTYR | |
| SCHEMBL11252465 | 1.00 | P2RY6 (0.49) | P2RY6P2RY14NT5ETYMSTYR | |
| SCHEMBL11248727 | 1.00 | P2RY6 (0.49) | P2RY6P2RY14NT5ETYMSTYR | |
| SCHEMBL11246189 | 0.90 | P2RY6 (0.50) | P2RY6P2RY14NT5ETYMSTSHR | |
| SCHEMBL11246184 | 0.90 | P2RY6 (0.50) | P2RY6P2RY14NT5ETYMSTSHR | |
| SCHEMBL9638269 | 0.90 | P2RY6 (0.50) | P2RY6P2RY14NT5ETYMSTSHR | |
| SCHEMBL9638270 | 0.90 | P2RY6 (0.50) | P2RY6P2RY14NT5ETYMSTSHR | |
| SCHEMBL11230072 | 0.90 | P2RY6 (0.46) | P2RY6P2RY14NT5ETYMSTSHR | |
| SCHEMBL11230068 | 0.90 | P2RY6 (0.46) | P2RY6P2RY14NT5ETYMSTSHR | |
| SCHEMBL11242245 | 0.89 | P2RY6 (0.45) | P2RY6P2RY14NT5ETYMSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340728-A | ANTITUMOR AGENT OF 5-FLUORO URIDINE OR URACIL DERIVATIVE | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-07-20 | — | — | US | disclosed |