Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 6/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.50 |
| ▸ | NT5E | P21589 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | HINT1 | P49773 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.41 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638269 | 1.00 | P2RY6 (0.50) | P2RY6P2RY14NT5ETSHRLMNA | |
| SCHEMBL11246184 | 1.00 | P2RY6 (0.50) | P2RY6P2RY14NT5ETSHRLMNA | |
| SCHEMBL9638270 | 1.00 | P2RY6 (0.50) | P2RY6P2RY14NT5ETSHRLMNA | |
| SCHEMBL9638063 | 0.93 | CTSB (0.46) | P2RY6P2RY14NT5ETSHRLMNA | |
| SCHEMBL9638061 | 0.93 | CTSB (0.46) | P2RY6P2RY14NT5ETSHRLMNA | |
| SCHEMBL8670319 | 0.93 | P2RY6 (0.48) | P2RY6P2RY14NT5ETSHRLMNA | |
| SCHEMBL11240778 | 0.93 | P2RY6 (0.48) | P2RY6P2RY14NT5ETSHRLMNA | |
| SCHEMBL9637176 | 0.91 | CYP3A4 (0.47) | P2RY6P2RY14NT5ETSHRLMNA | |
| SCHEMBL9637173 | 0.91 | CYP3A4 (0.47) | P2RY6P2RY14NT5ETSHRLMNA | |
| SCHEMBL11248724 | 0.90 | P2RY6 (0.49) | P2RY6P2RY14NT5ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340728-A | ANTITUMOR AGENT OF 5-FLUORO URIDINE OR URACIL DERIVATIVE | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-07-20 | — | — | US | disclosed |