Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 15/20 | 0.58 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422901 | 0.88 | PDE7A (0.63) | PDE7APDE7BSLC6A4MAPTSMN1; SMN2 | |
| SCHEMBL15155301 | 0.88 | PDE7A (0.60) | PDE7APDE7BMAPTSMN1; SMN2MEN1 | |
| SCHEMBL1193561 | 0.85 | PDE7A (0.50) | PDE7APDE7BSLC6A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL11495179 | 0.82 | PDE7A (0.51) | PDE7APDE7BMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8490515 | 0.81 | PDE7A (0.69) | PDE7APDE7BSLC6A4MAPTSMN1; SMN2 | |
| SCHEMBL1193378 | 0.79 | PDE7A (0.49) | PDE7ASLC6A4MAPTSMN1; SMN2MEN1 | |
| SCHEMBL2419394 | 0.78 | PDE7A (0.56) | PDE7APDE7BMAPTSMN1; SMN2MEN1 | |
| SCHEMBL6949538 | 0.78 | MAPT (0.50) | PDE7ASLC6A4MAPTMEN1ALDH1A1 | |
| SCHEMBL30605799 | 0.77 | PDE7A (0.86) | PDE7APDE7BSLC6A4MAPTSMN1; SMN2 | |
| SCHEMBL866726 | 0.77 | PDE7A (0.86) | PDE7APDE7BSLC6A4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327018-A | Azo dyes and the production and use thereof | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| US-4185018-A | Process for producing benzofurazan-1-oxides | CIBA-GEIGY CORPORATION (US) | 1980-01-22 | — | — | US | disclosed |