Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.48 |
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543017 | 0.87 | PBRM1 (0.48) | ADORA3HAVCR2HSD17B10CA12RNASEH1 | |
| SCHEMBL11541951 | 0.80 | HAVCR2 (0.52) | ADORA3HAVCR2HSD17B10ADORA2AADORA2B | |
| SCHEMBL11545191 | 0.74 | HAVCR2 (0.43) | ADORA3HAVCR2HSD17B10ADORA2AADORA2B | |
| SCHEMBL11543165 | 0.74 | ADORA3 (0.60) | ADORA3HAVCR2HSD17B10ADORA2AADORA2B | |
| SCHEMBL11255156 | 0.72 | ADORA3 (0.76) | ADORA3 | |
| Acetone SCHEMBL11543246 | 0.71 | ADORA3 (0.74) | ADORA3 | |
| Acetaldehyde SCHEMBL11543250 | 0.69 | ADORA3 (0.70) | ADORA3 | |
| SCHEMBL11547087 | 0.69 | ADORA3 (0.60) | ADORA3HAVCR2HSD17B10ADORA2AADORA2B | |
| SCHEMBL28313337 | 0.67 | HAVCR2 (0.51) | ADORA3HAVCR2HSD17B10ADORA2AADORA2B | |
| SCHEMBL11628215 | 0.67 | ADORA3 (0.64) | ADORA3HAVCR2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337255-A | ANTI-ALLERGY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4179561-A | REACTING A 3-DIAZOOXINDOLE WITH A SUBSTITUTED ACETYLENE | E. R. SQUIBB & SONS, INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4164578-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1979-08-14 | — | — | US | disclosed |
| US-4128644-A | ANTIALLERGENS, ANTIINFLAMMATORY PHOSPHODIESTERASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4112096-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4112098-A | ANTIALLERGENS, ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4076818-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |