SCHEMBL11248848

SCHEMBL11248848

O=P(OCCBr)(OCCBr)OCCOP(=O)(OCCBr)OCCBr

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
CYP3A4 P08684 2/20 0.43
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2141473 0.97 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHR
SCHEMBL10627755 0.84 ALDH1A1 (0.75) ALDH1A1CYP3A4TSHR
SCHEMBL715639 0.84 TSHR (0.65) ALDH1A1CYP3A4TSHR
SCHEMBL28542418 0.80 ALDH1A1 (0.36) ALDH1A1CYP3A4
SCHEMBL31403212 0.80 CYP3A4 (0.39) ALDH1A1CYP3A4TSHR
SCHEMBL93504 0.80 ALDH1A1 (0.42) ALDH1A1CYP3A4
Ethylene SCHEMBL11248838 0.80 ALDH1A1 (0.36) ALDH1A1CYP3A4
SCHEMBL27792863 0.80 CYP3A4 (0.77) CYP3A4TSHR
SCHEMBL3691036 0.79 CYP3A4 (0.55) ALDH1A1CYP3A4TSHR
SCHEMBL3680820 0.77 CYP3A4 (0.52) ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE30887-E HALOGENATED PHOSPHATE ESTERS OLIN CORPORATION (US) 1982-03-23 US claimed
US-RE30887-E HALOGENATED PHOSPHATE ESTERS OLIN CORPORATION (US) 1982-03-23 US disclosed