Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240578 | 0.86 | CYP3A4 (0.36) | KMT2ANPY5RCYP3A4RAB9AMEN1 | |
| SCHEMBL213721 | 0.83 | CYP3A4 (0.40) | KMT2ANPY5RCYP3A4RAB9AMEN1 | |
| SCHEMBL29735596 | 0.83 | CYP3A4 (0.40) | KMT2ANPY5RCYP3A4RAB9AMEN1 | |
| SCHEMBL11228890 | 0.82 | KMT2A (0.36) | KMT2ANPY5RRAB9AMEN1MAPT | |
| SCHEMBL11235691 | 0.81 | CNR2 (0.36) | KMT2ANPY5RMAPTSMN1; SMN2LMNA | |
| SCHEMBL11240811 | 0.80 | MAPT (0.35) | KMT2ACYP3A4RAB9AMEN1MAPT | |
| SCHEMBL9185575 | 0.80 | CYP3A4 (0.35) | KMT2ANPY5RCYP3A4RAB9AMEN1 | |
| SCHEMBL11241233 | 0.80 | HTT (0.35) | KMT2ANPY5RCYP3A4RAB9AMEN1 | |
| SCHEMBL11369724 | 0.80 | CYP3A4 (0.42) | KMT2ACYP3A4RAB9AMEN1MAPT | |
| SCHEMBL9185712 | 0.80 | CYP3A4 (0.38) | KMT2ANPY5RCYP3A4RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |