Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235932 | 0.87 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL11244078 | 0.85 | MEN1 (0.36) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL11248860 | 0.82 | KMT2A (0.33) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| SCHEMBL11374754 | 0.82 | KMT2A (0.38) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL11242157 | 0.79 | MEN1 (0.35) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL11230933 | 0.79 | MEN1 (0.35) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL11241233 | 0.78 | HTT (0.35) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL11243224 | 0.77 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL11235691 | 0.77 | CNR2 (0.36) | KMT2ALMNANPY5RCNR2MAPT | |
| SCHEMBL11241792 | 0.77 | CNR2 (0.41) | KMT2AMEN1ALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |