Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1196453 | 1.00 | CA1 (0.45) | CA1CA2ALDH1A1MAPTKDM4E | |
| SCHEMBL12144965 | 0.91 | CA1 (0.41) | CA1CA2ALDH1A1MAPTKDM4E | |
| SCHEMBL1196279 | 0.88 | CA1 (0.43) | CA1CA2ALDH1A1MAPTKDM4E | |
| SCHEMBL18806637 | 0.86 | ALDH1A1 (0.40) | CA1CA2ALDH1A1MAPTKDM4E | |
| SCHEMBL1195373 | 0.85 | CA1 (0.41) | CA1CA2ALDH1A1HPGDTSHR | |
| SCHEMBL5516744 | 0.84 | CA1 (0.41) | CA1CA2ALDH1A1TSHR | |
| SCHEMBL1196002 | 0.83 | CA1 (0.42) | CA1CA2ALDH1A1MAPTGAA | |
| SCHEMBL5521743 | 0.83 | PPARG (0.42) | CA1CA2ALDH1A1MAPTTSHR | |
| SCHEMBL5524445 | 0.83 | PPARG (0.42) | CA1CA2ALDH1A1MAPTTSHR | |
| SCHEMBL5523877 | 0.83 | PPARG (0.42) | CA1CA2ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322435-A | FOR THROMBOSIS | SANKYO COMPANY LIMITED (JP) | 1982-03-30 | — | — | US | disclosed |