Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230146 | 0.83 | MEN1 (0.40) | ALDH1A1NPSR1EPHX2GAAHSD17B10 | |
| SCHEMBL25933146 | 0.80 | ALDH1A1 (0.55) | ALDH1A1BPTFSMN1; SMN2HSD11B1NPSR1 | |
| SCHEMBL13660316 | 0.72 | ALDH1A1 (0.50) | ALDH1A1BPTFSMN1; SMN2HSD11B1P2RX7 | |
| SCHEMBL12321006 | 0.70 | ALDH1A1 (0.45) | ALDH1A1BPTFSMN1; SMN2HSD11B1NPSR1 | |
| SCHEMBL11559800 | 0.69 | ALDH1A1 (0.47) | ALDH1A1BPTFSMN1; SMN2HSD11B1NPSR1 | |
| SCHEMBL16722815 | 0.69 | GAA (0.58) | ALDH1A1GAAHSD17B10TSHR | |
| SCHEMBL1478949 | 0.69 | ALDH1A1 (0.57) | ALDH1A1BPTFSMN1; SMN2HSD11B1NPSR1 | |
| SCHEMBL1072911 | 0.69 | ALDH1A1 (0.61) | ALDH1A1BPTFSMN1; SMN2HSD11B1NPSR1 | |
| SCHEMBL3021927 | 0.68 | ALDH1A1 (0.59) | ALDH1A1BPTFSMN1; SMN2HSD11B1NPSR1 | |
| SCHEMBL5252701 | 0.68 | ALDH1A1 (0.54) | ALDH1A1BPTFSMN1; SMN2HSD11B1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361577-A | ANTIULCER AND LUTEOLYTIC AGENTS | CARLO ERBA - S.P.A. (IT) | 1982-11-30 | — | — | US | disclosed |
| US-4169145-A | ANTIULCER AGENTS, LUTEOLYTIC ABORTIFACIENTS, OXYTOCICS | CARLO ERBA S.P.A. (IT) | 1979-09-25 | — | — | US | disclosed |
| US-4035415-A | GASTROINTESTINAL DISORDERS | CARLO ERBA, S.P.A. (IT) | 1977-07-12 | — | — | US | disclosed |