Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | NPC1 | O15118 | 3/20 | 0.81 |
| ▸ | RAB9A | P51151 | 3/20 | 0.81 |
| ▸ | CDK4 | P11802 | 6/20 | 0.70 |
| ▸ | CCND1 | P24385 | 6/20 | 0.70 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.67 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331421 | 0.90 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9ACDK4 | |
| Cyanide SCHEMBL31484737 | 0.86 | MEN1 (0.92) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL14303574 | 0.85 | MEN1 (0.90) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL1514510 | 0.84 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL11246728 | 0.81 | MEN1 (0.70) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL15047821 | 0.81 | MEN1 (0.82) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL28448761 | 0.81 | MEN1 (0.77) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL28906084 | 0.81 | NPC1 (0.78) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL13942340 | 0.80 | MEN1 (0.81) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL17232881 | 0.80 | MC5R (0.83) | MEN1KMT2AMAPTBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350634-A | HYPOTENSIVE AGENTS | SANDOZ LTD. (CH) | 1982-09-21 | — | — | US | disclosed |
| EP-0000355-B1 | NEW INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | SANDOZ AG (CH) | 1982-01-06 | — | — | EP | disclosed |