Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | ACHE | P22303 | 3/20 | 0.66 |
| ▸ | CDK4 | P11802 | 7/20 | 0.61 |
| ▸ | CCND1 | P24385 | 7/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331421 | 0.83 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AACHE | |
| SCHEMBL11249035 | 0.81 | MEN1 (0.81) | MEN1KMT2ANPC1RAB9AACHE | |
| SCHEMBL11280301 | 0.81 | MEN1 (0.71) | MEN1KMT2ACDK4CCND1POLB | |
| SCHEMBL2614252 | 0.80 | SIGMAR1 (0.68) | NPC1RAB9A | |
| Cyanide SCHEMBL31484737 | 0.80 | MEN1 (0.92) | MEN1KMT2ANPC1RAB9AACHE | |
| SCHEMBL14303574 | 0.79 | MEN1 (0.90) | MEN1KMT2ANPC1RAB9AACHE | |
| SCHEMBL1514510 | 0.78 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL19411633 | 0.77 | MEN1 (0.67) | MEN1KMT2ANPC1RAB9ACDK4 | |
| SCHEMBL7019674 | 0.76 | ACHE (0.66) | MEN1KMT2ANPC1RAB9AACHE | |
| SCHEMBL11250970 | 0.76 | SLC6A4 (0.71) | MEN1KMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350634-A | HYPOTENSIVE AGENTS | SANDOZ LTD. (CH) | 1982-09-21 | — | — | US | claimed |
| EP-0000355-B1 | NEW INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | SANDOZ AG (CH) | 1982-01-06 | — | — | EP | claimed |
| EP-0000355-A1 | New indole derivatives, processes for their preparation, and pharmaceutical compositions containing them. | SANDOZ AG (CH) | 1979-01-24 | — | — | EP | claimed |
| US-4350634-A | HYPOTENSIVE AGENTS | SANDOZ LTD. (CH) | 1982-09-21 | — | — | US | disclosed |
| EP-0000355-B1 | NEW INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | SANDOZ AG (CH) | 1982-01-06 | — | — | EP | disclosed |
| EP-0000355-A1 | New indole derivatives, processes for their preparation, and pharmaceutical compositions containing them. | SANDOZ AG (CH) | 1979-01-24 | — | — | EP | disclosed |