Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 8/20 | 0.49 |
| ▸ | CA12 | O43570 | 7/20 | 0.49 |
| ▸ | CA2 | P00918 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CD69 | Q07108 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022962 | 0.98 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL16620453 | 0.98 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL12975857 | 0.98 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL23133262 | 0.98 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL13697192 | 0.98 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL23563178 | 0.98 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL15596615 | 0.98 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL4409830 | 0.98 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL18814012 | 0.98 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL8432075 | 0.98 | CA9 (0.51) | CA9CA12CA2CA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072734-B | Uridine derivative and method for preparing doxifluridine medicament by using same | 中国科学院昆明植物研究所 | 2023-04-07 | — | — | CN | disclosed |
| CN-111100172-B | Cytosidine derivative and method for preparing capecitabine medicine from same | 中国科学院昆明植物研究所 | 2023-03-17 | — | — | CN | disclosed |
| CN-111100172-A | Cytosidine derivative and method for preparing capecitabine medicine from same | 中国科学院昆明植物研究所 | 2020-05-05 | — | — | CN | disclosed |
| CN-111072734-A | Uridine derivative and method for preparing doxifluridine medicament by using same | 中国科学院昆明植物研究所 | 2020-04-28 | — | — | CN | disclosed |
| US-4340729-A | 5'-Deoxy-5-fluorouridine | HOFFMANN-LA ROCHE INC. (US) | 1982-07-20 | — | — | US | disclosed |