Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 8/20 | 0.51 |
| ▸ | CA12 | O43570 | 7/20 | 0.51 |
| ▸ | CA2 | P00918 | 7/20 | 0.51 |
| ▸ | CA1 | P00915 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022962 | 1.00 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL8432075 | 1.00 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL12975857 | 1.00 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL16620453 | 1.00 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL23563178 | 1.00 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL15596615 | 1.00 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL23133262 | 1.00 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL18814012 | 1.00 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL13697192 | 1.00 | CA9 (0.51) | CA9CA12CA2CA1TSHR | |
| SCHEMBL14268499 | 1.00 | CA9 (0.51) | CA9CA12CA2CA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220041641-A1 | QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION | SENDA BIOSCIENCES INC (US) | 2022-02-10 | — | — | US | disclosed |
| EP-3891751-A1 | QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION | Senda Biosciences, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020118238-A1 | QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION | KINTAI THERAPEUTICS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |
| US-20130012466-A1 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-10 | — | — | US | disclosed |
| US-20120245054-A1 | High-Throughput Assay for Sugar-Mediated Drug Transport | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-09-27 | — | — | US | disclosed |
| US-8232254-B2 | Colchicine glycosylated to include a sugar moiety on a methoxyamino-appended colchicine; cytolysis equivalent to paclitaxel and doxorubicin; stabilizers of tubulin formation; anticarcinogenic -arthritic agents; Mediterranean fever, amyloidosis, scleroderma, irritable bowel syndrome or gout | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-31 | — | — | US | disclosed |
| US-8211654-B2 | High-throughput assay for sugar-mediated drug transport | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-03 | — | — | US | disclosed |
| US-20090317829-A1 | High-throughput assay for sugar-mediated drug transport | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-12-24 | — | — | US | disclosed |
| US-20080171787-A1 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-07-17 | — | — | US | disclosed |
| EP-0553297-B1 | PROCESS FOR THE PREPARATION OF GLYCOSYL PHOSPHATE TRIESTERS | DU PONT (US) | 1995-01-25 | — | — | EP | disclosed |
| US-5288859-A | Reacting metal azide with glycosyl phosphate triester | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-02-22 | — | — | US | disclosed |
| EP-0553297-A1 | PROCESS FOR THE PREPARATION OF GLYCOSYL PHOSPHATE TRIESTERS. | DU PONT (US) | 1993-08-04 | — | — | EP | disclosed |
| WO-1992009612-A1 | PROCESS FOR THE PREPARATION OF GLYCOSYL PHOSPHATE TRIESTERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |
| US-5095123-A | Phosphorylation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171787-A1 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | TUBB6, TUBB, TUBA1C | CA9 2179/4885CA12 975/4885CA2 3733/4885 |
| US-20220041641-A1 | QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION | SLC10A2, SLC10A1, BCAT2 | CA9 508/4885CA12 1858/4885CA2 284/4885 |
| US-20130012466-A1 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | TUBB6, TUBB, TUBA1C | CA9 2179/4885CA12 975/4885CA2 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.